Thrombolytic use in select stroke patients with recent direct oral anticoagulant (DOAC) ingestion did not raise the risk of the most feared bleeding complication, according to the largest-yet ...

The prevalence of inappropriate direct oral anticoagulant (DOAC) dosing in patients with atrial fibrillation (AF) was 25%. Several demographic factors such as advanced age, presence of chronic kidney ...

Adoption of DOAC population management tool dashboard before July 2018 linked to decline in off-label dosing prescriptions HealthDay News — Early adoption of the direct oral anticoagulant (DOAC) ...

Despite concerns about the potential bleeding risk, IV thrombolysis could be safely given to ischemic stroke patients within a day of direct oral anticoagulant (DOAC) therapy, according to ...

In a recent study published in JAMA Network Open, researchers compared outcomes related to three direct oral anticoagulant (DOAC) care models to prevent anticoagulation-associated adverse effects ...

In patients with atrial fibrillation with low thrombosis risk but high bleeding risk, both standard- and low-dose DOACs are equally effective and safe. Standard-dose direct oral anticoagulant therapy ...

The risk for death goes up for patients with atrial fibrillation (AF) who are put on direct oral anticoagulants (DOAC) at dosages other than those approved for stroke prevention, whether higher or ...

Study authors assessed the effectiveness and safety of DOACs compared with warfarin in patients with valvular atrial fibrillation. People with valvular atrial fibrillation (AF) who are new users of ...

Among patients hospitalized for atrial fibrillation (AF) or flutter, prescription of an off-label dose of a direct oral anticoagulant (DOAC) at discharge remains relatively common, according to data ...

Patients with atrial fibrillation (AF) who use a direct oral anticoagulant (DOAC) dose that’s inconsistent with US Food and Drug Administration labeling—a practice believed, in many cases, to be ...

Swedish cohort study shows 13% (95% CI, 2-22%) lower risk of kidney function decline or kidney failure and 12% (95% CI, 3-20%) lower risk of acute kidney injury with use of direct oral anticoagulants ...

In a trial of patients undergoing urologic surgeries, resuming DOACs on postoperative day 1 at a low dose was associated with an acceptable risk of bleeding events. The PAUSE-URO trial’s perioperative ...