Historically, these factors have made the identification of proteins incredibly challenging. The advent of mass spectrometry (MS) and MS-based proteomics helped to change that. 2 MS is an analytical ...

Structural mass spectrometry has emerged as a powerful approach to elucidate the three‐dimensional conformations of proteins and their complexes under near‐physiological conditions. In particular, ...

Just like workers need the right environment to efficiently perform their tasks, proteins require placement within specific cellular compartments to function properly. Therefore, understanding the ...

Researchers at the University of California, San Francisco have identified an iron-storing protein called ferritin light ...

A screening technique commonly used in drug discovery can yield important details about the actions of molecular ‘glues’ in protein interactions. Molecular glues are emerging as powerful therapeutic ...

Antibody arrays: removal of high abundance proteins is not required, but antibody availability limits protein detection. Mass spectrometry: “hypothesis-free” protein detection is affected by high ...

In this webinar, Dr. Johann Stojko, experienced biophysicist at Novalix, will present integrated workflows that combine ...

Thermo Fisher Scientific has developed a new antibody testing and verification methodology using Immunoprecipitation-Mass Spectrometry (IP-MS) that is designed to help researchers, antibody producers ...

Chemical cross-linking (XL) is widely used to investigate protein–protein interactions (PPIs), including transient or low ...

The process of protein identification typically begins with a bottom-up approach, where proteins are enzymatically digested—most commonly with trypsin—into smaller peptides. These peptides are ...