Resistant and severe hypertension represent a growing global health burden and are associated with a markedly increased risk of cardiovascular, renal, and ...

Renin-independent aldosterone production is associated with rapid kidney function decline in adults with hypertension, according to new data.

Aldosterone synthase (CYP11B2) is the key enzyme responsible for the final steps in aldosterone production, a steroid hormone that plays a critical role in the regulation of electrolyte balance and ...

Spironolactone is a medication that can reduce fluid retention. It’s often prescribed to treat high blood pressure and heart failure. It blocks the action of the hormone aldosterone, which may affect ...